Metabolic Health

Diabetes and obesity are driven by interconnected changes in glucose homeostasis, insulin signalling, adipocyte biology, lipid metabolism and inflammation. Screening one endpoint in isolation can therefore miss the mechanism—or create a misleading picture of efficacy. Boveevo builds functional metabolic models that allow candidates to be assessed across complementary biological processes, from 3T3-L1 adipogenesis and GLUT translocation to insulin responsiveness and glucose uptake in HepG2 cells. By combining phenotypic and molecular readouts, we help identify compounds or ingredients that show meaningful metabolic activity and create a rational evidence base for lead selection, biomarker development and subsequent in vivo validation.

In Vitro Services

✔️ 3T3-L1 adipogenesis

✔️ Lipid accumulation / Oil Red O

✔️ GLUT translocation

✔️ Insulin potency responsiveness

✔️ Glucose uptake

✔️ HepG2 glucose uptake

✔️ PPAR / C/EBP pathway assays

✔️ Insulin-signalling Western blot

In Vivo Services

✔️ STZ-Induced Diabetes Model

✔️ High-Fat Diet (HFD)-Induced Obesity Model

✔️ db/db Mouse Model

✔️ ob/ob Mouse Model

✔️ Treadmill Exercise / Endurance Model

✔️ Swimming Endurance Model